Fantasy football season is in full swing and your first pick could be the make or break pick of your draft. If you hit a home run, you’re sitting pretty, but if you strike out, you’re behind the eight ball. Those are a lot of mixed metaphors to tell you to make your decision wisely!

Bijan Robinson, Saquon Barkley and Jahmyr Gibbs lead my Top 75 fantasy football running back rankings for the 2025 season. Christian McCaffrey and Derrick Henry round out my Top 5. Ashton Jeanty, Kyren Williams,

Chuba Hubbard enters 2025 fantasy football drafts as a volume-driven RB2 after back-to-back strong seasons leading the Panthers’ backfield.

The second (of two) tight ends in this two-round mock draft is Trey McBride, who was Kyler Murray’s favorite target last year. While his well-document woes at finding the end zone finally ended in Week 17, McBride hauled in 111 receptions on his way to finishing as the TE2 last year, something that should be his floor in 2025.

Joey Pollizze's fantasy football bold predictions for 2025. His top fantasy football projections and calls, including for Christian McCaffrey, Justin Fields, and more.

SportsLine simulated the NFL season 10,000 times and revealed its 2025 Fantasy football sleepers for 2025 Fantasy football draft prep